阳葵,$2.生长调节剂对甾体微生物催化转化过程的影响[J].分子催化,1999,(2):137-139 |
生长调节剂对甾体微生物催化转化过程的影响 |
Effect of Growth Regulator on Microbial Catalytic Transformation of Steroid |
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DOI: |
中文关键词: 生长调节剂 微生物转化 催化 羟化酶 甾体激素 |
英文关键词:Steroid, Microbial transformation, Catalytic activity |
基金项目:国家自然科学青年基金,天津市21世纪青年科学基金 |
阳葵 $2 |
[1]天津大学理学院 [2]天津大学化工学院 |
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中文摘要: |
利用微生物菌种(如绿僵菌Metarhiziumsp)产生的11α-羟化酶,催化甾体底物16α,17α-环氧黄体酮(16α,17α-epoxy-4-pregnene-3,20-dione)羟化转化为产物11α-羟基-16α,17α-环氧黄体酮,是当前甾... |
英文摘要: |
The effect of addition of growth regulator into the microbial catalytic transformation system of steroid was investigated. It was shown that the proper concentration of growth regulator is 0.025%. Addition of proper quantity of growth regulator greatly enhanced the growth yield and the catalytic transformation activity of mold, when steroid substrate was added after 42 h of cultivation. This effect may be accounted for the ability of the growth regulator spreading itself into the cells in the nonionic form. |
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