| 张安林,许慧,潘春跃,邓泽平,彭媛媛.手性聚醚催化烯烃的高对映选择性环氧化反应研究[J].分子催化(中英文),2020,34(6):514-524 |
| 手性聚醚催化烯烃的高对映选择性环氧化反应研究 |
| Highly Enantioselective Asymmetric Epoxidation of Olefins Catalyzed by Chiral Polyethers |
| 投稿时间：2020-08-24 修订日期：2020-09-16 |
| DOI： |
| 中文关键词: ee值 苯乙烯 回收 不对称环氧化 聚醚 |
| 英文关键词:enantiomeric excess styrene recovery asymmetric catalysis polyether |
| 基金项目:国家自然科学基金（GrantNo.21674129，21636010）；中央引导地方科技发展专项（2018CT5006）；湖南省创新创业科技投资项目（2018GK5002） |
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| 中文摘要: |
| 以单噁唑啉和环氧氯丙烷为原料，可以成功制备一系列结构稳定并带有可调节位阻侧链的均相固载型聚醚催化剂.固载型聚醚结构保证了催化剂能均匀地分散在大多数有机介质中，增强了其对有机底物的吸附性和配位作用，显著提高了其在有机溶剂中的催化活性.聚醚催化剂成功催化了烯烃在四氢呋喃中的不对称环氧化反应，对映选择性好，收率高（ee值高达98%，收率高达96%）.此外，该聚醚催化剂可以很容易地被回收和循环使用至少10次，而催化活性不会出现显著地降低. |
| 英文摘要: |
| Based on a series of stable polyethers derived from single oxazolines and epichlorohydrins, the immobilized homogeneouscatalysts with adjustable steric hindrance of the oxazoline side chains have been successfully prepared. Polyether-immobilized structure ensures that the catalysts can be well dispersed in most of organic medium, which enhances the adsorption and coordination of organic substrate and significantly improves the reactivity in solvent. The polyether-catalysts have successfully catalyzed the asymmetric epoxidation of olefins in tetrahydrofuran with high enantio-selectivity and yield(up to 98% ee and 96% yield). Moreover, the catalysts can be easily recovered and recycled at least ten times without significant loss of catalytic activity. |
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