孙立瑞,辛嘉英,刘丰源,张宏迪,李家柔,夏春谷.新型非均相催化剂纳米金属杂化酶的研究进展[J].分子催化,2019,33(3):274-284 |
新型非均相催化剂纳米金属杂化酶的研究进展 |
Progress of Novel Heterogeneous Enzyme/Metal Nanoparticle Hybridase |
投稿时间:2019-03-28 修订日期:2019-04-20 |
DOI: |
中文关键词: 非均相催化剂 杂化酶 纳米金属杂化酶 纳米催化 |
英文关键词:heterogeneous catalyst hybridase enzyme/metal nanoparticle biohybrids nanocatalysis |
基金项目:国家自然科学基金(21573055);哈尔滨商业大学创新团队项目(YJSCX2018-481HSD) |
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中文摘要: |
随着生物技术、电子传感技术、纳米技术的发展,新型非均相催化剂-纳米金属杂化酶的研究和开发逐渐走进学者们的视野.纳米金属杂化酶不仅具有高催化活性、高稳定性,并且可以在一定程度上改善原酶的底物特异性、化学选择性、立体选择性及区域选择性等,同时可提高酶的可操作性,便于重复利用.我们就纳米金属杂化酶的设计与合成策略、金属纳米粒子的种类、表征方法、杂化酶的特征及应用等方面进行综述报道,希望可以为学者们提供新的思路和思考,促进多学科的融合发展. |
英文摘要: |
With the development of biotechnology, electronic sensing technology and nanotechnology, the research and development of a new heterogeneous catalyst, enzyme/metal nanoparticle biohybrids, have gradually attracted close attention. The enzyme/metal nanoparticles biohybrids not only have high catalytic activity and stability, but also can improve the substrate specificity, chemo-, regio-, and enantioselectivity, and easy to be reused and separated from the reaction system. In this paper, the design and synthesis strategies, the types of metal nanoparticles, the characterization methods, the characteristics and applications of hybrid enzymes have been reviewed. We hoped to provide new ideas for scholars and promote the development of multidisciplinary integration. |
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